पुरुष बन्ध्याकरण या पुरुष नसबंदी या वासेक्टोमी (Vasectomy), पुरुषों के लिए शल्यक्रिया द्वारा बन्ध्याकरण प्रक्रिया है। इस क्रिया से पुरुषों की शुक्रवाहक नलिका अवरुद्ध कर दी जाती है जिससे शुक्राणु वीर्य के साथ पुरुष लिंग तक नहीं पहुँच सकें।

Vasectomy is an elective surgical procedure that results in male sterilization, often as a means of permanent contraception. During the procedure, the male vasa deferentia are cut and tied or sealed so as to prevent sperm from entering into the urethra and thereby prevent fertilization of a female through sexual intercourse. Vasectomies are usually performed in a physician's office, medical clinic, or, when performed on a non-human animal, in a veterinary clinic. Hospitalization is not normally required as the procedure is not complicated, the incisions are small, and the necessary equipment routine.